What is Naloxone

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1 min 44 sec
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Naloxone: Reversing Opioid Overdose

Understanding Naloxone

Naloxone belongs to a class of drugs known as opioid receptor antagonists. These medications actively compete with opioids for the receptors they target in the body.

Action and Effectiveness

Role as an Antagonist:

  • Naloxone binds to opioid receptors, blocking the effects of opioids and rapidly reversing their impact.
  • It is specifically effective in treating opioid overdoses but does not work for other types of drug overdoses, such as methamphetamine, cocaine, or Diazepam.
  • Safety: If mistakenly administered to someone not experiencing an opioid overdose, naloxone has no harmful effects.

Forms and Availability

Options for First Aid:

  • Naloxone is available in three forms for first aid use: pre-dosed injection, ampoule injection, and nasal spray.
  • These forms ensure flexibility in administering the drug quickly and effectively.

Naloxone Availability in the UK

Accessibility and Usage:

  • Naloxone is distributed across the UK, primarily in pre-dosed syringes or nasal spray, targeting individuals at risk of opioid overdose.
  • Training Importance: Training for individuals close to those at risk is crucial, enabling them to administer naloxone promptly when needed.
  • After administering naloxone, document the details and retain the used equipment for handover to Emergency Medical Services (EMS) upon their arrival.